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Chlorotripyrrolidinophosphonium hexafluorophosphate CAS:133894-48-1

Chlorotripyrrolidinophosphonium hexafluorophosphate, also known as PyAOP, is a chemical compound commonly used as a coupling reagent in peptide synthesis and other amide bond-forming reactions. This phosphonium-based reagent plays a crucial role in organic synthesis, particularly in peptide chemistry, due to its ability to activate carboxylic acids, forming highly reactive acylating intermediates and facilitating efficient and selective amide bond formation. Its unique structure and reactivity make it valuable in the production of peptides for research, pharmaceutical, and biotechnological applications.


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Application and Effect:

In addition to its essential role in peptide synthesis, PyAOP has significant applications in medicinal chemistry and drug discovery. It is utilized in the preparation of active pharmaceutical ingredients (APIs) and drug conjugates, contributing to the efficient synthesis of pharmaceutical compounds with improved pharmacokinetic and pharmacodynamic properties. The compound's versatile nature makes it valuable in the development of novel drugs and therapeutic agents. Furthermore, PyAOP finds application in materials science, particularly in surface functionalization and the creation of bioconjugates. Its capacity to form stable intermediates and compatibility with various substrates make it a valuable reagent for modifying surfaces and synthesizing functional materials. In the field of biotechnology, PyAOP is utilized in the development of advanced materials for biomedical applications, contributing to advancements in areas such as drug delivery systems, biomaterials, and biosensors. The versatile nature of Chlorotripyrrolidinophosphonium hexafluorophosphate, along with its pivotal role in organic synthesis, medicinal chemistry, and material science, underscores its importance in diverse scientific and industrial fields. Ongoing research and utilization of PyAOP continue to drive advancements in peptide chemistry, pharmaceutical synthesis, and material engineering, further solidifying its status as a valuable and multifaceted chemical reagent.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C12H24ClF6N3P2
Assay 99%
Appearance white powder
CAS No.  133894-48-1
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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