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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1233501-65-9

Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride is a chemical compound distinguished by a pyrrolidine ring substituted with an ethyl group at the 3-position and a tert-butyl group at the 1-position. This compound has garnered attention in medicinal chemistry due to its structural complexity and potential pharmacological applications. Its unique configuration presents opportunities for designing novel drug candidates with specific biological targets, making it a valuable asset in drug discovery and development endeavors.


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Application and Effect:

Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride exhibits intricate structural features and holds promise in medicinal chemistry and pharmaceutical research. 1. Medicinal Chemistry: Biological Targets: The arrangement of functional groups in this compound suggests potential interactions with various biological targets, including receptors, enzymes, or transporters. These interactions can modulate physiological processes, making it a versatile scaffold for drug design targeting a wide range of diseases. Cardiovascular Disorders: Compounds with pyrrolidine scaffolds have shown promise in modulating cardiovascular function and pathways implicated in heart diseases. Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate derivatives could exhibit similar activities, making them valuable in the development of treatments for conditions such as hypertension or arrhythmias. 2. Drug Development: Structure Optimization: Synthetic modifications of the pyrrolidine core and substituent groups enable structure-activity relationship (SAR) studies, facilitating the design of analogs with improved pharmacokinetic properties and enhanced target affinity. Metabolic Stability: The tert-butyl group at the 1-position may enhance the compound's metabolic stability, potentially prolonging its half-life and improving its efficacy as a therapeutic agent. 3. Synthetic Chemistry: Versatile Synthesis: Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride can be synthesized through various routes, allowing for the exploration of synthetic strategies and the creation of diverse analogs for biological evaluation. Chiral Synthesis: The synthesis of enantiomerically pure derivatives of this compound enables the study of their pharmacological properties and may lead to the development of drugs with improved selectivity and reduced side effects. 4. Biological Evaluation: Preclinical Studies: Derivatives of this compound undergo thorough preclinical evaluation to assess their pharmacological activities, pharmacokinetics, and safety profiles. This data guides further optimization and preclinical development towards clinical trials. In summary, Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride represents a promising scaffold in medicinal chemistry, offering opportunities for the development of novel therapeutic agents targeting various diseases, particularly cardiovascular disorders. Its unique structural features and potential pharmacological activities make it a valuable tool in drug discovery and development efforts. Continued research and optimization are essential to fully exploit its therapeutic potential and translate findings into clinical applications.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C12H23ClN2O4
Assay 99%
Appearance white powder
CAS No.  1233501-65-9
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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