Clevidipine butyrate CAS:167221-71-8

Clevidipine butyrate, an analog of clevidipine, is utilized extensively for its potent vasodilatory effects and favorable pharmacokinetic characteristics. Here are its key applications: Hypertensive Emergencies: Clevidipine butyrate is crucial in swiftly managing acute hypertensive crises in hospitalized patients. Its rapid action helps prevent organ damage associated with severe hypertension, ensuring prompt blood pressure control. Perioperative Blood Pressure Control: During surgical procedures, maintaining stable blood pressure is essential. Clevidipine butyrate's quick onset and short duration of action make it ideal for adjusting blood pressure levels efficiently, contributing to optimal surgical conditions and patient recovery. Intensive Care Units (ICUs): In critical care settings like ICUs, Clevidipine butyrate is employed for continuous blood pressure management in patients needing close monitoring. Its titratable infusion enables precise control, minimizing blood pressure fluctuations. Stroke Management: Clevidipine butyrate may be used in acute ischemic stroke management to prevent further neurological damage by maintaining blood pressure within therapeutic ranges. Its rapid onset ensures timely intervention. Cardiac Surgery: Patients undergoing cardiac procedures often experience blood pressure fluctuations. Clevidipine butyrate's rapid onset and short duration of action make it valuable for maintaining hemodynamic stability during and after surgery. Renal Impairment: Clevidipine butyrate's metabolism is independent of hepatic and renal function, making it suitable for patients with impaired kidney function. This characteristic ensures predictable pharmacokinetics and personalized dosing. Pregnancy-Induced Hypertension: In cases of hypertension induced by pregnancy, Clevidipine butyrate can safely manage elevated blood pressure levels, minimizing risks to both mother and fetus. Drug Compatibility: Clevidipine butyrate exhibits minimal interaction with other medications, making it suitable for patients with complex medication regimens or comorbidities requiring multiple drug therapies. In summary, Clevidipine butyrate is a valuable pharmaceutical in managing acute hypertension and perioperative blood pressure control. Its rapid onset, short duration of action, and precise titration capabilities contribute to its versatility across various clinical scenarios, ensuring effective blood pressure management and patient safety.