Concanavalin A CAS:11028-71-0 Manufacturer Price

Cell Agglutination: One of the notable effects of Con A is its ability to cause agglutination (clumping) of cells. This property has been useful for studying cell adhesion and cell surface interactions.

Glycoprotein Isolation: Con A binds specifically to glycoproteins that contain terminal mannose and glucose residues. This property has been exploited to isolate and purify glycoproteins from complex mixtures, such as biological fluids or cell lysates, by using Con A affinity chromatography.

Detection of Glycoproteins: Con A can be used to detect and quantify glycoproteins in samples. By using Con A conjugated with fluorescent or enzymatic tags, it is possible to visualize or measure the amount of glycoproteins present in a sample through fluorescence microscopy or enzyme-linked immunosorbent assay (ELISA) techniques, respectively.

Cell Surface Labeling: Due to its affinity for cell surface sugars, Con A can be used to label specific cell types or study glycosylation patterns on cell surfaces. Con A conjugated with fluorophores or other tags allows for the visualization and analysis of cells through techniques such as flow cytometry or fluorescence microscopy.

Immunomodulation: Con A has immunomodulatory properties and can affect the function of immune cells. It can stimulate the activation and proliferation of T lymphocytes, leading to the production of cytokines and other immune responses. This property has been explored in immunotherapy and vaccine development, where Con A has been used to enhance immune responses or modulate immune tolerance.

Research Tool: Con A is a widely used tool in various fields of biological research. It has been used to study carbohydrate-protein interactions, cell adhesion, glycosylation patterns, and immune responses. Its ability to bind to specific sugars makes it valuable for studying and manipulating glycoproteins and glycolipids.