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Curcumin 95% CAS:14639-25-9 Manufacturer Supplier

Curcumin, the active component of turmeric (Curcuma longa), has been regarded as an anti-inflammatory and antioxidant agent . Particularly, it can scavenge reactive oxygen species, such as hydroxyl radicals, superoxide anion radicals, and nitrogen dioxide radicals. Additionally, it serves as an anti-inflammatory by down-regulating the production of pro-inflammatory cytokines (e.g., IL-1 and TNF-α) and inhibiting the activation of specific transcription factors (e.g., NF-κB and AP-1). Curcumin also demonstrates antiproliferative properties. Specifically, it inhibits UV radiation-induced skin cancer in SKH-1 hairless mice and reduces UVB-induced matrix metalloproteinase-1/3 expression in human dermal fibroblasts via MAPK-p38/JNK pathway suppression.


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Application and Effect

Curcumin has been widely used in the food industry as a common natural pigment for a long time. It is mainly used for the dyeing of canned food, sausage products and soy sauce products. The amount of curcumin used is determined by normal production needs. The product form of functional food with curcumin as the main component can be general food or some non-food forms, such as capsules, pills or tablets. For general food form, some yellow pigmented foods can be considered, such as cakes, sweets, beverages, etc.Curcumin has been proved to inhibit the proliferation of a variety of tumor cells through regulating a variety of transcription factors (NF-κB, AP-1, etc.), mitogen-activated protein kinase (MAPK), growth factor receptor kinase (PDGFR, VEGFR, etc.), and cyclooxygenase. It plays an important role in the cell cycle and further to inhibit proliferation. Curcumin can also inhibit the migration of tumor cells by activating caspase and inducing tumor cell apoptosis.

Product Sample

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Product Packing:

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Additional Information:

Composition C21H20O6
Assay 95%
Appearance Orange Yellow Powder
CAS No. 458-37-7
Packing 25KG  
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

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