Cyclohexylmagnesium bromide CAS:931-50-0
Cyclohexylmagnesium bromide (C₆H₁₁MgBr) is a representative member of the Grignard reagents, which are pivotal in organic chemistry for forming carbon-carbon bonds. As a highly reactive organomagnesium compound, it features a cyclohexyl group bonded to a magnesium atom, which itself is coordinated to a bromine atom. These reagents are typically prepared by reacting magnesium metal with the corresponding alkyl or aryl halide, in this case, cyclohexyl bromide. One of the most significant applications of cyclohexylmagnesium bromide lies in its ability to act as a nucleophile. When introduced to electrophilic centers such as carbonyl groups, it can add to these sites to generate alcohols. For instance, it can effectively react with aldehydes and ketones, resulting in secondary and tertiary alcohols, respectively. This reaction pathway is vital for constructing more complex molecules, making it invaluable in synthetic organic chemistry. Furthermore, cyclohexylmagnesium bromide has been explored for its reactivity with other electrophiles, including esters and nitriles. Its nucleophilic character enables it to participate in various coupling reactions, contributing to the formation of larger carbon frameworks essential for pharmaceuticals and complex organic materials. The use of cyclohexylmagnesium bromide is not without its challenges; it reacts vigorously with water and moisture, necessitating anhydrous conditions during handling and storage. Safety precautions must be taken due to its flammability and the potential hazards associated with organometallic compounds. In summary, cyclohexylmagnesium bromide is a versatile and powerful reagent in the field of organic synthesis. Its unique properties enable chemists to construct complex organic molecules through carbon-carbon bond formation, significantly impacting pharmaceuticals, material science, and industrial chemistry. Understanding its reactivity and applications can enhance synthetic strategies and contribute to advancements in chemical research.
Composition | C6H11BrMg |
Assay | 99% |
Appearance | white powder |
CAS No. | 931-50-0 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |