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Cyclosporin A CAS:59865-13-3 Manufacturer Price

Cyclosporin A, commonly known as cyclosporine or CsA, is a medication used primarily in organ transplant recipients to prevent the rejection of transplanted organs. It is an immunosuppressive drug that works by suppressing the activity of the immune system, specifically T cells, which are responsible for mounting an immune response against foreign substances or transplanted organs.

Cyclosporin A is commonly used in cases of kidney, liver, heart, lung, and pancreas transplants, as well as in some autoimmune diseases like rheumatoid arthritis and psoriasis. By dampening the immune system response and inhibiting the production of certain cytokines, it helps to prevent the destruction of transplanted organs or the progression of certain autoimmune disorders.


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Application and Effect

Immunosuppression: Cyclosporin A is primarily used as an immunosuppressive agent. It suppresses the activity of the immune system, particularly T cells, which helps prevent the rejection of transplanted organs. This immunosuppressive effect is also useful in treating autoimmune diseases like rheumatoid arthritis or psoriasis where the immune system attacks the body's own cells.

Organ Transplants: Cyclosporin A is widely used in solid organ transplantation, such as kidney, liver, heart, lung, or pancreas transplants. It is usually given in combination with other immunosuppressive drugs to prevent the recipient's immune system from attacking the transplanted organ.

Dosage and Monitoring: The dosage of cyclosporin A varies depending on factors like the individual's body weight, organ function, and response to the drug. Blood levels of cyclosporin A are regularly monitored to ensure therapeutic levels are maintained without causing toxicity. These levels can also guide dosage adjustments for optimal effectiveness.

Autoimmune Disorders: Besides organ transplantation, cyclosporin A can be prescribed for certain autoimmune conditions, such as rheumatoid arthritis and psoriasis, to reduce the overactivity of the immune system and alleviate symptoms. In these cases, lower doses are usually required compared to transplant recipients.

Product Packing:

试剂包装2

Additional Information:

Composition C62H111N11O12
Assay 99%
Appearance White powder
CAS No. 59865-13-3
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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