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Degarelix CAS:214766-78-6

Degarelix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of advanced prostate cancer. It works by rapidly suppressing the production of testosterone, a hormone that fuels the growth of prostate tumors.


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Application and Effect:

Degarelix is indicated for the management of advanced prostate cancer, particularly in cases where hormonal therapy is warranted. Unlike GnRH agonists, which initially cause a surge in testosterone before reducing its levels, degarelix rapidly and effectively suppresses the production of this hormone without causing an initial surge. This immediate action can help mitigate the potential exacerbation of symptoms associated with prostate cancer, such as pain or urinary obstruction, resulting from the temporary increase in testosterone levels observed with agonist therapy. The medication is typically administered through subcutaneous injection, allowing for controlled release over an extended period. By inhibiting the binding of GnRH to its receptors in the pituitary gland, degarelix reduces the secretion of luteinizing hormone and follicle-stimulating hormone, which are responsible for stimulating testosterone production by the testes. This ultimately leads to a rapid decrease in testosterone levels within the body, helping to slow the progression of prostate cancer and alleviate associated symptoms. Degarelix offers a valuable alternative for patients with advanced prostate cancer who require androgen deprivation therapy. Its ability to promptly lower testosterone levels without causing an initial surge may be particularly beneficial for individuals at higher risk of experiencing disease-related complications or those requiring urgent symptom relief. In addition to its use in the initial treatment of advanced prostate cancer, degarelix may also be employed in the context of neoadjuvant therapy prior to radiation therapy or prostatectomy, or as an adjuvant therapy following these interventions. Its role in combination therapy underscores its potential to contribute to comprehensive and personalized approaches for managing prostate cancer across different stages and clinical scenarios. Side effects of degarelix may include injection site reactions, hot flashes, fatigue, and changes in liver enzyme levels; however, these are generally well-tolerated and manageable. Regular monitoring and supportive care are essential components of patient management to ensure optimal outcomes and adherence to the prescribed treatment regimen. In summary, degarelix represents a crucial tool in the management of advanced prostate cancer, offering a rapid and effective means of lowering testosterone levels to slow the progression of the disease and alleviate associated symptoms. Close collaboration between healthcare providers and patients is essential for integrating degarelix into the overall treatment plan, tailoring therapy to individual needs, and addressing potential side effects to optimize the balance between therapeutic efficacy and quality of life.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C82H103ClN18O16
Assay 99%
Appearance white powder
CAS No.  214766-78-6
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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