DICHLORO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM (II) CAS:134524-84-8

DICHLORO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM (II) finds extensive applications as a catalyst in asymmetric synthesis, playing a pivotal role in the production of chiral compounds with high enantiomeric purity. In asymmetric hydrogenation reactions, this complex catalyzes the addition of hydrogen to unsaturated substrates, yielding chiral products with excellent stereoselectivity. By virtue of its chiral ligands, it enables the synthesis of optically active intermediates and fine chemicals essential in the pharmaceutical and agrochemical industries. Moreover, DICHLORO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM (II) is utilized in asymmetric allylic substitution reactions, where it promotes the substitution of allylic electrophiles with nucleophiles in a stereocontrolled manner. This process allows for the efficient construction of complex molecules bearing stereogenic centers with high enantioselectivity. Additionally, the compound serves as a catalyst in asymmetric cycloaddition reactions, facilitating the formation of chiral cyclic compounds with precise control over stereochemistry. Such transformations are valuable in the synthesis of natural products and pharmaceutical candidates, where chirality plays a crucial role in biological activity and pharmacological properties. Furthermore, DICHLORO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM (II) is employed in asymmetric ring-opening reactions of epoxides and aziridines, enabling the synthesis of enantioenriched compounds widely used as synthetic intermediates and building blocks in organic chemistry. Beyond its applications in small molecule synthesis, this complex contributes to the development of chiral ligands for other transition metal catalysts, enhancing their stereocontrol and catalytic efficiency in asymmetric transformations. Overall, DICHLORO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM (II) plays a crucial role in asymmetric catalysis, offering synthetic chemists powerful tools for the construction of complex chiral molecules with high efficiency and precision. Its applications span various industries, driving innovation in drug discovery, materials science, and chemical synthesis.