Ethyl 3-(pyridin-3-yl)acrylate CAS:28447-17-8

Ethyl 3-(pyridin-3-yl)acrylate is a chemical compound with a conjugated acrylate group attached to a pyridine ring, offering unique properties for various applications in organic synthesis and materials science. This molecule combines the reactivity of an acrylate moiety with the aromaticity of the pyridine ring, making it valuable for constructing diverse molecular structures with potential applications in pharmaceuticals, agrochemicals, and functional materials.

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Application and Effect:

As a versatile building block, this molecule enables efficient synthesis of pharmaceuticals and biological probes. Reactions at the ester construct targeted amides and acids. Modifications of the piperidine ring or benzyl group systematically introduce diversity. The hydrochloride salt enhances stability and solubility for reactions and screening. These transformations rapidly furnish focused libraries applicable for drug discovery. The benzyl ether also improves solubility during optimization stages. It can serve as a monomer for polymer synthesis. Moreover, selective deprotections offer routes to agrichemical prototypes. Therefore, through strategic manipulation of its distinct reactive sites, this synthon supports synthesis of drugs, polymers, and agrochemicals.