Evodia Rutaecarpa PE CAS:2420-56-6 Manufacturer Supplier

Evodiamine is a naturally occurring indole alkaloid, being the main bioactive component of Evodia rutaecarpa. It has various kinds of pharmacological activities including anti-tumor, protecting the heart, causing weight loss and anti-inflammatory, analgesic and anti-senile dementia. Evodiamine, as a natural anti-cancer drug, can inhibit the proliferation of a variety of tumor cells, including cervical cancer, colon cancer, lung cancer, melanoma, T lymphocytic leukemia, prostate cancer and breast cancer.

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Evodiamine can reduce the activity of intracellular cyclic adenosine monophosphate (cAMP)-related pathways, inhibit the activity of 3β-HSD and other steroid-related enzymes, reduce and influence signal transduction and RNA activation Protein (StAR) expression. It can directly take effect on the rat cortical adrenal cortex mesh cell for inhibition of corticosterone secretion. Evodiamine can inhibit the proliferation of a variety of tumor cells, including cervical cancer, colon cancer, lung cancer, melanoma, T lymphocytic leukemia, prostate cancer and breast cancer.In addition, evodiamine has good binding capability to a variety of proteins, so it can be used as a multi-target compound to play a variety of biological activity.