Triethyl orthoacetate, with the chemical formula C₈H₁₄O₃, is an important reagent in organic synthesis, particularly in the fields of medicinal chemistry and materials science. As a member of the orthoester family, it features three ethyl groups attached to an acetic acid-derived moiety. Triethyl orthoacetate is often utilized as a versatile building block for synthesizing various organic compounds, including esters, ketones, and heterocycles. Its ability to undergo hydrolysis and condensation reactions makes it a useful tool for chemists exploring diverse synthetic pathways. Additionally, its role in the preparation of pharmaceuticals highlights its significance in drug discovery and development.