Boc-Trp-OSu, or N-tert-butoxycarbonyl-L-tryptophan N-hydroxysuccinimide ester, is a valuable compound widely used in peptide synthesis and bioconjugation chemistry. This reagent consists of Boc-protected tryptophan coupled to an N-hydroxysuccinimide (NHS) ester group, making it a versatile tool for the selective modification of amino groups in peptides and proteins. Boc-Trp-OSu is utilized in various bioconjugation strategies, enabling the site-specific attachment of peptides to targeting molecules, surfaces, or other biomolecules for biomedical research and therapeutic applications.