Fmoc-Arg(Tos)-OH CAS:83792-47-6
Fmoc-Arg(Tos)-OH plays a crucial role in peptide synthesis, particularly when precise protection of the guanidine nitrogen in arginine is required. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the tosyl group on the guanidine nitrogen provides an additional layer of protection. Researchers utilize Fmoc-Arg(Tos)-OH for synthesizing peptides with specific guanidine modifications, influencing their biological activities. The dual protection approach enables controlled manipulation of guanidine reactivity, making this compound valuable in designing peptides for antimicrobial studies, bioconjugation, and medicinal chemistry. The compatibility of Fmoc-Arg(Tos)-OH with standard peptide synthesis methods, including solid-phase peptide synthesis (SPPS), enhances its utility. This compound finds application in constructing peptides for biological assays, drug discovery, and the development of peptide-based materials. Controlled removal of protecting groups allows for the strategic incorporation of arginine with modified guanidine, contributing to the diversity of peptides that can be synthesized. In summary, Fmoc-Arg(Tos)-OH stands as a specialized and versatile tool in peptide chemistry, empowering researchers to explore and modify guanidine reactivity for a range of scientific and therapeutic applications.
Composition | C28H30N4O6S |
Assay | 99% |
Appearance | white powder |
CAS No. | 83792-47-6 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |