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Fmoc-Asn(Trt)-OH CAS:132388-59-1

Fmoc-D-Asn-OH, or Fmoc-D-asparagine, is a significant derivative in peptide synthesis, featuring a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the D-enantiomer of asparagine. This compound plays a pivotal role in solid-phase and solution-phase peptide synthesis, selectively protecting the amino group of D-asparagine for controlled peptide chain elongation. Fmoc-D-Asn-OH is recognized for its compatibility with various coupling reagents and solid supports, contributing to its importance in the realm of peptide chemistry.


Product Detail

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Application and Effect:

Fmoc-Asn(Trt)-OH holds a central position in peptide synthesis, particularly in the controlled assembly of asparagine-containing peptides. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the trityl group provides an additional layer of protection. Researchers extensively employ Fmoc-Asn(Trt)-OH in the synthesis of peptides for various applications, including drug development, biomaterials, and the design of bioactive peptides. Its compatibility with standard peptide synthesis methodologies, both in solid-phase and solution-phase strategies, enhances its utility in diverse research endeavors. The controlled removal of protecting groups allows for the strategic incorporation of asparagine into peptide sequences, contributing to the diversity of peptides that can be synthesized. Moreover, Fmoc-Asn(Trt)-OH finds utility in the synthesis of peptides for proteomics research and the study of cellular processes. The strategic use of the trityl protection group enables precise manipulation of asparagine reactivity, offering researchers a valuable tool for designing peptides with specific modifications. In summary, Fmoc-Asn(Trt)-OH stands as a versatile and indispensable tool in peptide chemistry, empowering researchers to explore and modify asparagine reactivity for a wide range of scientific applications.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C38H32N2O5
Assay 99%
Appearance white powder
CAS No.  132388-59-1
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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