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Fmoc-Asp(OBut)-OH CAS:71989-14-5

Fmoc-Asp(OBut)-OH, or Fmoc-aspartic acid with O-butyl (OBut) protection, is a key component in peptide synthesis. This derivative features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the aspartic acid molecule, with an additional O-butyl group safeguarding the carboxyl group. Fmoc-Asp(OBut)-OH plays a crucial role in peptide chemistry, offering enhanced selectivity during peptide chain elongation and controlled manipulation of the aspartic acid carboxyl group.


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Application and Effect:

Fmoc-Asp(OBut)-OH is a versatile tool in peptide synthesis, especially in crafting peptides containing aspartic acid with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the O-butyl group adds an extra layer of protection to the carboxyl group. Researchers extensively employ Fmoc-Asp(OBut)-OH in synthesizing peptides for various applications, including drug development, biomaterials, and designing bioactive peptides with specific structural features. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. The controlled removal of protecting groups allows strategic incorporation of aspartic acid into peptide sequences, expanding the range of synthesizable peptides. Furthermore, Fmoc-Asp(OBut)-OH finds utility in synthesizing peptides for proteomics research and studying cellular processes. The strategic use of the O-butyl protection group enables precise manipulation of aspartic acid reactivity, offering researchers a valuable tool for designing peptides with tailored modifications. In summary, Fmoc-Asp(OBut)-OH stands as a fundamental and indispensable tool in peptide chemistry, empowering researchers to explore and modify aspartic acid reactivity for a broad range of scientific applications, particularly focusing on peptides containing this essential amino acid.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C23H25NO6
Assay 99%
Appearance white powder
CAS No.  71989-14-5
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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