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Fmoc-Asp(OBut)-OSu CAS:78553-23-8

Fmoc-Asp(OBut)-OSu, or Fmoc-aspartic acid with O-butyl (OBut) protection and N-hydroxysuccinimide (OSu) ester functionality, is a pivotal compound in peptide synthesis. This derivative features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the aspartic acid molecule, with an additional O-butyl group safeguarding the carboxyl group and an OSu ester group facilitating efficient coupling reactions. Fmoc-Asp(OBut)-OSu plays a crucial role in peptide chemistry, offering enhanced selectivity during peptide chain elongation and controlled manipulation of the aspartic acid carboxyl group.


Product Detail

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Application and Effect:

Fmoc-Asp(OBut)-OSu serves as a versatile tool in peptide synthesis, particularly in crafting peptides containing aspartic acid with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the O-butyl group adds an extra layer of protection to the carboxyl group. The OSu ester functionality facilitates efficient and selective amide bond formation during peptide coupling reactions. Researchers extensively employ Fmoc-Asp(OBut)-OSu in synthesizing peptides for various applications, including drug development, biomaterials, and designing bioactive peptides with specific structural features. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. The controlled removal of protecting groups allows strategic incorporation of aspartic acid into peptide sequences, expanding the range of synthesizable peptides. Furthermore, Fmoc-Asp(OBut)-OSu finds utility in synthesizing peptides for proteomics research and studying cellular processes. The strategic use of the O-butyl protection group enables precise manipulation of aspartic acid reactivity, and the OSu ester group facilitates bioconjugation and labeling of peptides. In summary, Fmoc-Asp(OBut)-OSu stands as a fundamental and indispensable tool in peptide chemistry, empowering researchers to explore and modify aspartic acid reactivity for a broad range of scientific applications, particularly focusing on peptides with enhanced functionalization through the OSu ester group.

Product Sample:

Amino acid powder1
Amino acid powder2

Product Packing:

Amino acid powder3
Amino acid powder4
Amino acid powder5
Amino acid powder6

Additional Information:

Composition C27H28N2O8
Assay 99%
Appearance white powder
CAS No.  78553-23-8
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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