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Fmoc-D-Asn(Trt)-OH CAS:180570-71-2

Fmoc-D-Asn(Trt)-OH, or Fmoc-D-asparagine with trityl (Trt) protection, is a pivotal component in peptide synthesis. This derivative comprises a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the D-enantiomer of asparagine, with an additional trityl group guarding the amino group. Fmoc-D-Asn(Trt)-OH holds significance in peptide chemistry, offering enhanced selectivity during peptide chain elongation and controlled manipulation of the D-asparagine amino group.

 


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Application and Effect:

Fmoc-D-Asn(Trt)-OH is instrumental in peptide synthesis, especially in crafting peptides containing the D-enantiomer of asparagine with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the trityl group adds an extra layer of protection. Researchers utilize Fmoc-D-Asn(Trt)-OH extensively in synthesizing peptides for various applications, including drug development, biomaterials, and designing bioactive peptides with specific stereochemical configurations. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. The controlled removal of protecting groups allows strategic incorporation of D-asparagine into peptide sequences, expanding the repertoire of synthesizable peptides. Furthermore, Fmoc-D-Asn(Trt)-OH finds utility in synthesizing peptides for proteomics research and studying cellular processes. The strategic use of the trityl protection group enables precise manipulation of D-asparagine reactivity, offering researchers a valuable tool for designing peptides with tailored modifications. In summary, Fmoc-D-Asn(Trt)-OH stands as a versatile and indispensable tool in peptide chemistry, empowering researchers to explore and modify D-asparagine reactivity for a broad range of scientific applications, particularly focusing on peptides containing D-amino acids.

Product Sample:

Amino acid powder1
Amino acid powder2

Product Packing:

Amino acid powder3
Amino acid powder4
Amino acid powder5
Amino acid powder6

Additional Information:

Composition C38H32N2O5
Assay 99%
Appearance white powder
CAS No.  180570-71-2
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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