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Fmoc-D-Asp(OBut)-OH CAS:112883-39-3

Fmoc-D-Asp(OBut)-OH, or Fmoc-D-aspartic acid with O-butyl (OBut) protection, is a crucial compound in peptide synthesis. This derivative features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the D-enantiomer of aspartic acid, with an additional O-butyl group safeguarding the carboxyl group. Fmoc-D-Asp(OBut)-OH plays a pivotal role in peptide chemistry, offering enhanced selectivity during peptide chain elongation and controlled manipulation of the D-aspartic acid carboxyl group.


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Application and Effect:

Fmoc-D-Asp(OBut)-OH serves as a fundamental component in peptide synthesis, particularly in crafting peptides containing the D-enantiomer of aspartic acid with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the O-butyl group adds an extra layer of protection to the carboxyl group. Researchers extensively utilize Fmoc-D-Asp(OBut)-OH in synthesizing peptides for various applications, including drug development, biomaterials, and designing bioactive peptides with specific structural features. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. The controlled removal of protecting groups allows strategic incorporation of D-aspartic acid into peptide sequences, expanding the range of synthesizable peptides. Furthermore, Fmoc-D-Asp(OBut)-OH finds utility in synthesizing peptides for proteomics research and studying cellular processes. The strategic use of the O-butyl protection group enables precise manipulation of D-aspartic acid reactivity, offering researchers a valuable tool for designing peptides with tailored modifications. In summary, Fmoc-D-Asp(OBut)-OH stands as a versatile and indispensable tool in peptide chemistry, empowering researchers to explore and modify D-aspartic acid reactivity for a broad range of scientific applications, particularly focusing on peptides containing this essential amino acid.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C23H25NO6
Assay 99%
Appearance white powder
CAS No.  112883-39-3
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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