Fmoc-D-Cys(Trt)-OH CAS:167015-11-4

Fmoc-D-Cys(Trt)-OH serves as a foundational tool in peptide synthesis, especially in crafting peptides containing the D-enantiomer of cysteine with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the trityl group adds an extra layer of protection to the thiol group. Researchers extensively utilize Fmoc-D-Cys(Trt)-OH in synthesizing peptides for various applications, including the development of peptide-based therapeutics, biomaterials, and peptides with specific structural motifs. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. The controlled removal of protecting groups allows strategic incorporation of D-cysteine into peptide sequences, broadening the scope of synthesizable peptides. Furthermore, Fmoc-D-Cys(Trt)-OH finds utility in studies related to protein engineering, disulfide bond formation, and peptide conjugation reactions. The strategic use of the trityl protection group enables precise manipulation of D-cysteine reactivity, offering researchers a valuable tool for designing peptides with tailored modifications. In summary, Fmoc-D-Cys(Trt)-OH stands as a versatile and indispensable tool in peptide chemistry, empowering researchers to explore and modify D-cysteine reactivity for a broad range of scientific applications, particularly focusing on peptides containing this essential amino acid in the D-configuration.