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Fmoc-D-Gln-OH CAS:71989-20-3

Fmoc-D-Gln-OH, or Fmoc-D-glutamine, is a pivotal component in peptide synthesis. This compound features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the D-enantiomer of glutamine. Fmoc-D-Gln-OH plays a crucial role in peptide chemistry, providing enhanced selectivity during peptide chain elongation and controlled manipulation of the glutamine side chain in its D-form.


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Application and Effect:

Fmoc-D-Gln-OH serves as a specialized tool in peptide synthesis, specifically designed for crafting peptides containing D-glutamine with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the incorporation of the D-enantiomer adds a unique dimension to the synthesized peptides. Researchers extensively employ Fmoc-D-Gln-OH in synthesizing peptides for various applications, including studies involving D-amino acids, peptide-based therapeutics, and bioactive peptides with specific structural motifs. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. The controlled removal of protecting groups allows strategic incorporation of D-glutamine into peptide sequences, expanding the possibilities for synthesizing peptides with altered stereochemistry. Furthermore, Fmoc-D-Gln-OH finds utility in studies related to peptidomimetics, where the use of D-amino acids can impart enhanced stability and altered bioactivity to the synthesized peptides. The strategic use of Fmoc-D-Gln-OH enables precise manipulation of D-glutamine reactivity, offering researchers a valuable tool for designing peptides with unique stereochemical features. In summary, Fmoc-D-Gln-OH stands as a specialized and indispensable tool in peptide chemistry, empowering researchers to explore and modify D-glutamine reactivity for specific scientific applications, particularly focusing on peptides containing this enantiomeric form of the essential amino acid.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C20H20N2O5
Assay 99%
Appearance white powder
CAS No.  71989-20-3
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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