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Fmoc-Glu(But)-NH2 CAS:104090-92-8

Fmoc-Glu(But)-NH2, or Fmoc-glutamic acid with butyl (But) protection and an amino group (NH2), is a significant compound in peptide synthesis. This derivative features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the glutamic acid molecule, with an additional butyl group safeguarding the carboxyl group. The presence of the amino group adds versatility for downstream peptide modifications, making Fmoc-Glu(But)-NH2 a valuable building block in peptide chemistry.


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Application and Effect:

Fmoc-Glu(But)-NH2 serves as a versatile tool in peptide synthesis, offering researchers the ability to incorporate glutamic acid with precise control and flexibility. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the butyl group adds an extra layer of protection to the carboxyl group. Researchers extensively employ Fmoc-Glu(But)-NH2 in synthesizing peptides for various applications, including the design of peptide mimetics, peptide conjugation, and the development of bioactive peptides. The amino group allows for further functionalization, enabling the attachment of various molecules, fluorophores, or other moieties to tailor the properties of the synthesized peptides. Moreover, Fmoc-Glu(But)-NH2 finds utility in studies related to peptide-based drug development, as the butyl protection group enhances the stability and controlled release of the incorporated glutamic acid. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in diverse research endeavors. In summary, Fmoc-Glu(But)-NH2 stands as a fundamental and indispensable tool in peptide chemistry, providing researchers with a versatile building block for the synthesis of tailored peptides with specific functionalities, particularly focusing on peptides containing glutamic acid.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C24H28N2O5
Assay 99%
Appearance white powder
CAS No.  104090-92-8
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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