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Fmoc-Glu(OBut)-OH CAS:71989-18-9

Fmoc-Glu(OBut)-OH, or Fmoc-glutamic acid with butyl (OBut) protection, is a key component in peptide synthesis. This compound features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group attached to the glutamic acid molecule, with an additional butyl group safeguarding the carboxyl group. Fmoc-Glu(OBut)-OH plays a vital role in peptide chemistry, providing enhanced selectivity during peptide chain elongation and controlled manipulation of the glutamic acid carboxyl group.


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Application and Effect:

Fmoc-Glu(OBut)-OH serves as a versatile tool in peptide synthesis, particularly in crafting peptides containing glutamic acid with precision. The Fmoc protecting group shields the amino group, ensuring selective reactions during peptide coupling, while the butyl group adds an extra layer of protection to the carboxyl group. Researchers extensively employ Fmoc-Glu(OBut)-OH in synthesizing peptides for diverse applications, including drug development, biomaterials, and designing bioactive peptides with specific structural features. Its compatibility with standard peptide synthesis methodologies, in both solid-phase and solution-phase strategies, enhances its versatility in various research endeavors. The controlled removal of protecting groups allows strategic incorporation of glutamic acid into peptide sequences, expanding the range of synthesizable peptides. Furthermore, Fmoc-Glu(OBut)-OH finds utility in the study of cellular processes, neuropeptide synthesis, and the development of peptide-based therapeutics. The strategic use of the butyl protection group enables precise manipulation of glutamic acid reactivity, offering researchers a valuable tool for designing peptides with tailored modifications. In summary, Fmoc-Glu(OBut)-OH stands as a fundamental and indispensable tool in peptide chemistry, empowering researchers to explore and modify glutamic acid reactivity for a broad range of scientific applications, particularly focusing on peptides containing this essential amino acid.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C24H27NO6
Assay 99%
Appearance white powder
CAS No.  71989-18-9
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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