Geldanamycin CAS:30562-34-6
Although geldanamycin has demonstrated anti-cancer activity in laboratory studies, its clinical use is limited due to challenges related to toxicity and stability. Research efforts are ongoing to develop derivatives and analogs of geldanamycin with improved pharmacokinetic properties and reduced side effects for potential therapeutic applications. In experimental settings, geldanamycin and its derivatives have been investigated for their ability to inhibit Hsp90 function, leading to the degradation of client proteins involved in cancer cell growth and survival. This mechanism makes geldanamycin a promising candidate for targeted cancer therapy, particularly in cancers dependent on Hsp90-regulated pathways. Clinical trials exploring the efficacy and safety of geldanamycin derivatives in cancer patients are underway to evaluate their potential as anti-cancer agents. These studies aim to assess the drug's therapeutic benefits, optimal dosing regimens, response rates, and any associated adverse effects to determine their clinical utility in oncology practice. Collaboration between researchers, pharmaceutical companies, regulatory agencies, and healthcare providers is essential to advance the development of geldanamycin-based therapies and bring novel anti-cancer treatments to patients in need. Continued investigation into the pharmacological profile and clinical outcomes of geldanamycin derivatives holds promise for improving cancer treatment strategies and outcomes in the future.
Composition | C29H40N2O9 |
Assay | 99% |
Appearance | white powder |
CAS No. | 30562-34-6 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |