Germanium Sesquioxide CAS:12758-40-6 Manufacturer Supplier

Germanium Sesquioxide, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Germanium Sesquioxideis reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Germanium Sesquioxidealso exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Germanium Sesquioxide has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.