Glucomannan CAS:11078-31-2 Manufacturer Supplier

Glucomannan is a linear polysaccharide comprising 1,4-β-linked D-glucosyl and D-mannosyl residues, where the glucose:mannose (Glc:Man) ratio varies considerably. Konjac (Amorphophallus konjac) glucomannan has a Glc:Man ratio of approx. 2:3, Aloe vera glucomannan a ratio of 1:2, and salep (Orchis mureo) glucomannan has a ratio of approximately 1:4. All of the polysaccharides are acetylated, which imparts water solubility. Glucomannans are major cell-wall reserve carbohydrates in tubers of several plant genera. At certain stages in the development of the plants, the glucomannan is degraded and serves as an energy source.

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Application and Effect

Glucomannan is useful as a bulk laxative.Glucomannan improved blood lipid levels by enhancing fecal excretion of neutral sterol; and bile acids bind biliary salts, taking the blood lipids with them. In this application, the glucomannan has been found to be dangerous, leading to choking deaths of some consumers. This has led to a ban of these types of sweets in Europe and America, and a need for an accurate analytical procedure for glucomannan analysis.In several controlled trials, konjac glucomannan supported healthy lipid metabolism and triglyceride levels, possibly by promoting healthy bile acid secretion. Additionally, it supports healthy glucose utilization and vascular function to support overall cardiovascular health.