Glucomannan(Konjac) CAS:11078-31-2 Manufacturer Supplier

Glucomannan improved blood lipid levels by enhancing fecal excretion of neutral sterol; and bile acids bind biliary salts, taking the blood lipids with them.Lipid-lowering action may include an inhibition of cholesterol absorption in the jejunum (19) and bile acid absorption in the ileum (33) mediated by viscosity or less postprandial stimulation of 3-hydroxy3-methylglutaryl-CoA reductase.Raw glucomannan is thought to prolong gastric emptying time, which increases satiety, reduces body weight, decreases the ingestion of foods that increase cholesterol and glucose concentrations, reduces the postprandial rise in plasma glucose, suppresses hepatic cholesterol synthesis, and increases the fecal elimination of cholesterol-containing bile acids. There is no evidence that nonviscous versions more commonly marketed in the U.S. provide any health effects.