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GSSG CAS:27025-41-8 Manufacturer Price

GSSG, also known as oxidized glutathione, is the disulfide form of the antioxidant glutathione (GSH). While GSH is the reduced and active form, GSSG is the oxidized and inactive form. GSSG is formed when GSH donates its electrons to neutralize free radicals or other reactive species. This conversion helps protect the body against oxidative damage. GSSG can be converted back to GSH through a recycling process involving the enzyme glutathione reductase. Monitoring the ratio of GSH to GSSG in the body is useful in assessing the antioxidant status and overall health.


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Application and Effect

Biomarker of oxidative stress: Monitoring the GSSG/GSH ratio can serve as a biomarker to assess oxidative stress levels in the body. High GSSG levels have been associated with various diseases, including cardiovascular diseases, neurodegenerative disorders, and cancer.

Pharmacological research: Studying the GSSG effect and its impact on cellular functions can help in the development of pharmacological interventions to modulate oxidative stress. Targeting GSSG recycling and regulating the GSH/GSSG ratio can provide therapeutic benefits in various pathological conditions.

Antioxidant therapy: Understanding the GSSG effect can aid in the development of antioxidant therapies. By promoting the recycling of GSSG to GSH or supplementing with GSH precursors, such as N-acetyl cysteine (NAC), it is possible to restore the redox balance, reduce oxidative stress, and potentially alleviate related diseases.

Anti-aging strategies: Elevated oxidative stress and a disrupted GSH/GSSG ratio are associated with the aging process. By understanding the GSSG effect, researchers can explore strategies to maintain cellular redox balance and potentially slow down the aging process.

Product Packing:

试剂包装2

Additional Information:

Composition C20H32N6O12S2
Assay 99%
Appearance White powder
CAS No. 27025-41-8
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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