IBMX, 3-isobutyl-1-methylxanthine CAS:28822-58-4

3-isobutyl-1-methylxanthine, also known as IBMX, is a methylxanthine derivative that is commonly used in scientific research as a non-specific inhibitor of cyclic nucleotide phosphodiesterases. It is known to increase intracellular levels of cyclic AMP (cAMP) and cyclic GMP (cGMP) by inhibiting their breakdown, which can in turn modulate various cellular signaling pathways.

In addition to its research applications, IBMX has been used in some medical settings for its bronchodilator and vasodilator effects. However, its use in human medicine is limited.

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Application and Effect

Research Tool: IBMX is widely used in scientific research to increase intracellular levels of cAMP and cGMP, serving as a valuable tool for studying cellular signaling pathways, signal transduction, and pharmacological modulation of cyclic nucleotides.

Pharmacological Studies: IBMX is used in pharmacological studies to investigate the effects of elevated cAMP and cGMP levels on cellular function and physiological responses.

Adipocyte Differentiation: IBMX is known to enhance the differentiation of preadipocytes into mature adipocytes, and is frequently used in combination with other compounds to induce adipogenesis in cell culture experiments.

Vasodilator and Bronchodilator Effects: IBMX has been shown to exhibit vasodilator and bronchodilator effects, and has been studied for potential therapeutic applications in conditions such as asthma and pulmonary hypertension.

Modulation of Neuronal Activity: IBMX has been investigated for its role in modulating neuronal activity, synaptic transmission, and plasticity in the central nervous system.

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Additional Information:

Composition	C10H14N4O2
Assay	99%
Appearance	White powder
CAS No.	28822-58-4
Packing	Small and bulk
Shelf Life	2 years
Storage	Store in cool and dry area
Certification	ISO.