Ivabradine hydrochloride CAS:148849-67-6

Ivabradine hydrochloride is a pharmaceutical compound used primarily to reduce heart rate in patients with specific cardiovascular conditions. By selectively inhibiting the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the sinoatrial node of the heart, it reduces the heart rate without affecting myocardial contractility or ventricular repolarization. This medication is commonly employed for patients with chronic heart failure and impaired left ventricular systolic function who are in stable sinus rhythm with a resting heart rate of 70 beats per minute or more, despite optimal medical therapy. Additionally, Ivabradine hydrochloride may be prescribed for individuals with chronic stable angina pectoris who cannot tolerate or have contraindications to beta-blockers, or when beta-blockers are ineffective or inappropriate. It is important to note that Ivabradine hydrochloride should only be used under the supervision of a qualified healthcare professional due to potential side effects and individual variations in response to the medication. Dosage and administration should be determined by a healthcare provider based on the patient's specific condition and medical history.