Letrozole CAS:112809-51-5 Manufacturer Supplier
Letrazole can be synthesized in two steps from 4- bromomethyl-benzonitrile with 1,2,4-triazole and is a third generation aromatase inhibitor. It is a highly specific inhibitor of P450arom which prevents the conversion of androstenedione to estrone. The reduction of plasma estrogen was immediate and long lasting. This is accomplished with no inhibition of other steroid biosynthesis making it the most selective aromatase inhibitor tested. Letrazole has remarkable antitumor activity, is well tolerated and has no toxic side effects. It is 10,000 times more potent than aminoglutethimide, in vivo, the first well established aromatase inhibitor.
Composition | C17H11N5 |
Assay | 99% |
Appearance | White powder |
CAS No. | 112809-51-5 |
Packing | 25KG |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |
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