methyl 2-amino-6-(tert-butoxycarbonyl)hexanoate CAS:1372256-52-4

Methyl 2-amino-6-(tert-butoxycarbonyl)hexanoate serves as a key intermediate in peptide synthesis, where it is used to introduce the amino acid gamma-aminobutyric acid (GABA) into peptide sequences. Chemists utilize its Boc protecting group to safeguard the amino group during peptide chain assembly, allowing for selective deprotection and subsequent modification. In pharmaceutical research, Boc-GABA plays a crucial role in the development of peptide-based drugs targeting neurological disorders and other therapeutic areas. Peptide analogs containing GABA residues hold promise in the treatment of conditions such as epilepsy, anxiety, and sleep disorders, with Boc-GABA serving as a starting material for their synthesis. Furthermore, this compound finds application in the preparation of building blocks for combinatorial chemistry and drug discovery. By incorporating Boc-GABA into molecular scaffolds, researchers can generate libraries of diverse compounds for screening against biological targets, accelerating the identification of potential drug candidates. It's important to handle methyl 2-amino-6-(tert-butoxycarbonyl)hexanoate with appropriate safety measures, including proper ventilation, personal protective equipment, and adherence to established protocols for handling and disposal of chemical reagents. Ensuring safe laboratory practices is essential to prevent accidents and ensure the integrity of experimental results.