Berberine hydrochloride, also known as berberine hydrochloride, has long been used in clinical practice as a heat clearing, detoxification, and antibacterial drug. Commonly used in the treatment of bacterial dysentery, acute gastroenteritis, chronic cholecystitis, as well as ophthalmic conjunctivitis, suppurative chemobook otitis, and other diseases, all have significant therapeutic effects. Berberine hydrochloride is an isoquinoline alkaloid found in many plants, including 4 families and 10 genera of Berberidaceae. Berberine can precipitate yellow needle like crystals from ether.