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O,O’-di-tert-butyl-L-threonine acetate CAS:5854-77-3

O,O’-di-tert-butyl-L-threonine acetate is a chemical compound notable for its molecular structure, which includes a threonine backbone substituted with two tert-butyl groups and an acetate moiety. This compound is significant in organic chemistry due to its unique stereochemistry and potential applications in pharmaceutical and biochemical research. Synthesized through specialized organic synthesis techniques, O,O’-di-tert-butyl-L-threonine acetate serves as a versatile building block and intermediate in the development of novel pharmaceuticals and biochemical probes.


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Application and Effect:

O,O'-di-tert-butyl-L-threonine acetate exhibits distinctive chemical properties and applications, elucidated comprehensively below. Chemical Structure and Properties The compound features a threonine structure with two tert-butyl groups attached to the hydroxyl group of the threonine and an acetate group linked to the carboxyl group. This configuration influences its chemical behavior, including solubility, stability, and interactions with enzymes or receptors. The tert-butyl groups provide steric hindrance, affecting molecular recognition and reactivity, while the acetate group enhances solubility and modulates polarity. Synthesis Methods and Applications Synthesis of O,O'-di-tert-butyl-L-threonine acetate typically involves the selective protection of the hydroxyl group of threonine followed by esterification with acetic acid under controlled conditions. The process requires precise manipulation of reaction parameters to achieve high yield and purity, critical for its use in pharmaceutical and biochemical applications. Its synthesis pathway underscores its utility as a versatile intermediate in organic chemistry. Pharmaceutical and Biochemical Relevance In pharmaceutical research, this compound serves as a crucial intermediate for developing threonine-derived drugs or prodrugs designed to target specific biological pathways or disease mechanisms. Its structural modification with tert-butyl groups can enhance bioavailability and metabolic stability, making it a valuable scaffold for drug design. Moreover, in biochemical studies, O,O'-di-tert-butyl-L-threonine acetate acts as a probe to investigate enzyme kinetics or substrate specificity due to its tailored structural features. Biotechnological and Research Applications Beyond pharmaceuticals, this compound finds applications in biotechnological processes such as enzyme immobilization or chiral synthesis where its stereochemistry plays a pivotal role. The tert-butyl groups protect the threonine backbone while allowing selective modifications, enabling tailored functionalization for specific biotechnological needs. Conclusion O,O'-di-tert-butyl-L-threonine acetate represents a significant compound in organic chemistry, characterized by its intricate molecular structure and versatile applications in pharmaceutical and biochemical research. Its synthesis and use as an intermediate highlight ongoing advancements in organic synthesis methodologies and their application to address complex challenges in drug discovery and biotechnology. Future research efforts will likely focus on optimizing synthetic routes, exploring new pharmacological applications, and expanding its role in advancing biochemical understanding and therapeutic innovation.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C12H25NO3.C2H4O2
Assay 99%
Appearance white powder
CAS No.  5854-77-3
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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