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PhentolamineMesylate CAS:65-28-1

Phentolamine mesylate is a pharmaceutical salt derived from phentolamine, which belongs to the class of reversible α-adrenergic blockers. Its structure includes a methanesulfonate (mesylate) group. This compound is utilized for its pharmacological properties in the field of medicine and therapeutics.


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Application and Effect:

Phentolamine mesylate serves various crucial roles in clinical and research applications. As a potent vasodilator and antihypertensive agent, it is used in the treatment of hypertensive emergencies, particularly in cases of pheochromocytoma crisis, where prompt blood pressure reduction is essential. It also finds utility in managing iatrogenic catecholamine-induced hypertensive episodes during surgical procedures and other medical interventions. In dentistry, phentolamine mesylate is employed as a local anesthetic reversal agent, aiding in the management of soft tissue anesthesia following dental procedures involving local anesthetics containing a vasoconstrictor such as epinephrine. Its vasodilatory effects help in reducing local blood flow restriction and accelerating the recovery of normal tissue perfusion. Furthermore, this compound is utilized in diagnostic procedures such as the prevention and treatment of dermal necrosis caused by extravasation of vasoactive drugs, ensuring proper tissue perfusion. Additionally, it is involved in research studies and clinical trials exploring its potential applications in conditions related to vascular insufficiency, erectile dysfunction, and Raynaud's phenomenon, contributing to advancements in cardiovascular and urological medicine. Phentolamine mesylate's role extends to experimental settings as a tool in pharmacological and physiological research, aiding in the investigation of adrenergic receptor function, vascular responses, and the modulation of sympathetic nervous system activity. Its ability to block adrenergic receptors and influence vascular tone contributes to the understanding of cardiovascular physiology and the development of therapeutic interventions targeting adrenergic signaling pathways. Overall, phentolamine mesylate's diverse applications highlight its significance in clinical medicine, dentistry, research, and pharmaceutical development, underscoring its potential to contribute to the effective management of cardiovascular conditions and the advancement of scientific knowledge related to adrenergic receptor function and vascular regulation.

Product Sample:

Amino acid powder1
Amino acid powder2

Product Packing:

Amino acid powder3
Amino acid powder4
Amino acid powder5
Amino acid powder6

Additional Information:

Composition C18H23N3O4S
Assay 99%
Appearance white powder
CAS No.  65-28-1
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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