phosphoric acid tris-(2,2,2-trifluoro-ethyl) ester CAS:358-63-4

TFP is known for its ability to activate hydroxyl groups in organic compounds, facilitating the formation of ester or amide bonds. This makes it a valuable tool in peptide synthesis and other organic reactions where the coupling of functional groups is required. Additionally, TFP is used as a protecting group for alcohols and phenols in organic chemistry, allowing selective manipulation of these functional groups during multi-step synthesis processes. Its trifluoroethyl groups provide steric hindrance and electronic effects that can influence the reactivity and selectivity of chemical transformations. TFP is also utilized in the production of pharmaceuticals, agrochemicals, and specialty chemicals, where precise control over chemical reactions and functional group manipulation is essential. Furthermore, it finds applications in the modification of biomolecules, such as proteins and nucleic acids, for research and biotechnology purposes. Its versatility and reactivity make it a valuable tool in the field of organic synthesis and chemical biology.