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Potassium tert-butoxide CAS:865-47-4

Potassium tert-butoxide is a strong, non-nucleophilic base and a common reagent in organic synthesis. It is derived from potassium hydroxide and tert-butanol and appears as a white to off-white crystalline powder. In chemical reactions, it serves as a base due to its high basicity and is often employed in the deprotonation of various compounds, such as alcohols, phenols, and acidic protons adjacent to carbonyl groups. Additionally, it is utilized in the formation of carbon-carbon and carbon-heteroatom bonds, as well as in the synthesis of pharmaceuticals, agrochemicals, and materials chemistry.


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Application and Effect:

Potassium tert-butoxide finds extensive use as a powerful base and nucleophile in various organic transformations. It is commonly employed in the synthesis of ethers, esters, and amides through Williamson ether synthesis, esterification, and amidation reactions, respectively. Furthermore, it facilitates key processes such as Claisen condensation and Knoevenagel condensation, which are vital for the formation of carbon-carbon bonds in organic molecules. Its utility also extends to the preparation of β-diketones, enol ethers, and other valuable intermediates essential in organic synthesis. Moreover, it plays a crucial role in the field of pharmaceutical chemistry, enabling the efficient construction of complex molecular structures for the development of new drugs. Overall, the versatile applications of potassium tert-butoxide underscore its significance in organic chemistry and its pivotal role in the synthesis of diverse chemical compounds.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C4H9KO
Assay 99%
Appearance white powder
CAS No.  865-47-4
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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