4-tert-Butylbenzenesulfonyl chloride (4-tert-Butylbenzenesulfonyl chloride) is a common organic synthesis reagent with the formula C10H13ClO2S. As one of the sulfonyl chloride derivatives, it is often used in functional group protection and displacement reactions in organic synthesis. It can be used to synthesize amides, ethers, ketones and other compounds, common in the field of medicine and pesticide synthesis