Sodium t-butoxide is a strong, non-nucleophilic base commonly used in organic synthesis. It is derived from sodium hydroxide and t-butanol, and appears as a white to off-white crystalline powder. In chemical reactions, it serves as a base due to its high basicity and is often employed in the deprotonation of various compounds, such as alcohols, phenols, and acidic protons adjacent to carbonyl groups. Additionally, it is utilized in the formation of carbon-carbon and carbon-heteroatom bonds, as well as in the synthesis of pharmaceuticals, agrochemicals, and materials chemistry.