Rifampicin, also known as rifampin, is a broad-spectrum antibiotic medication belonging to the rifamycin group. It is widely used in the treatment of tuberculosis, leprosy, and other bacterial infections. Rifampicin works by inhibiting RNA synthesis in bacteria, thereby disrupting their ability to replicate and survive. Due to its potent antimicrobial activity and effectiveness against mycobacterial species, rifampicin is an essential component of combination therapy regimens for tuberculosis and other infectious diseases.