-
5-Azacytidine CAS:320-67-2
5-Azacytidine is a synthetic nucleoside analogue of cytidine that contains a nitrogen atom in the 5-position of the pyrimidine ring, replacing a carbon atom. This modification imparts unique pharmacological properties, making it an essential compound in molecular biology and cancer therapy. As a potent DNA methyltransferase inhibitor, 5-azacytidine can reactivate silenced genes by altering DNA methylation patterns, thereby influencing gene expression. Originally developed for treating hematologic malignancies, 5-azacytidine has gained attention for its potential applications in epigenetic therapy, regenerative medicine, and research targeting various diseases characterized by abnormal gene regulation.
-
2′-Fluoro-2′-deoxyuridine CAS:784-71-4
2′-Fluoro-2′-deoxyuridine (FdU) is a nucleoside analog of deoxyuridine, where the hydrogen atom at the 2′ position of the ribose sugar is replaced by a fluorine atom. This modification enhances the stability and bioactivity of the compound, making it valuable in biochemical research and therapeutic applications. FdU is particularly known for its role as an antiviral and anticancer agent, as it can interfere with DNA synthesis and inhibit the replication of certain viruses and cancer cells. Its unique properties make it a significant tool in the development of targeted therapies and molecular biology studies.
-
![4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one CAS:10212-20-1](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT260.png)
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one CAS:10212-20-1
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one is a complex nucleoside analog that features a pyrimidine base attached to a modified ribose sugar. The presence of a fluorine atom and hydroxyl groups in its structure enhances its biochemical properties, making it an interesting candidate for antiviral and anticancer research. This compound has potential applications in medicinal chemistry, particularly as a therapeutic agent targeting nucleic acid synthesis and metabolic pathways in pathogenic organisms. Its unique structural characteristics allow for better interaction with biological targets involved in DNA and RNA metabolism.
-
1,3,5-tri-O-benzoyl-alpha-D-ribofuranose CAS:22224-41-5
1,3,5-Tri-O-benzoyl-alpha-D-ribofuranose is a chemically modified form of ribose, featuring three benzoyloxy groups attached to the 1, 3, and 5 positions of the ribofuranose structure. This modification enhances its solubility and stability, making it useful in various synthetic applications in organic chemistry and biochemistry. As a protected derivative of ribose, it serves as an intermediate in the synthesis of nucleosides and nucleotides, critical components of RNA and DNA. Its unique properties make 1,3,5-tri-O-benzoyl-alpha-D-ribofuranose valuable for researchers seeking to develop novel therapeutic agents and materials in nucleotide chemistry.
-
2′-O-methyluridine CAS:2140-76-3
2′-O-Methyluridine is a naturally occurring nucleoside in which a methyl group is attached to the oxygen atom of the 2′ position of the ribose sugar in uridine. This modification enhances the stability and functionality of RNA molecules, making it a crucial component in various biological processes. 2′-O-Methyluridine plays significant roles in the structure and function of ribonucleic acids (RNAs), including messenger RNA (mRNA) and transfer RNA (tRNA). Its presence can influence RNA stability, translation efficiency, and interactions with proteins and other nucleic acids, making it an essential element in the study of molecular biology and therapeutic applications.
-
adenosine 5′-monophosphate sodium*from yeast CAS:4578-31-8
Adenosine 5′-monophosphate sodium (AMP) is a nucleotide derived from adenosine that plays a crucial role in cellular metabolism. AMP is essential for various biological processes, including energy transfer, signal transduction, and as a precursor for the synthesis of ATP and other nucleotides. The sodium salt form of AMP can be derived from yeast, which is rich in nucleotides due to its active metabolic pathways. This compound is commonly used in biochemistry and pharmacology as a biochemical reagent, food additive, and dietary supplement, owing to its potential health benefits and applications in promoting energy metabolism.
-
2′-Deoxycytidine CAS:951-77-9
2′-Deoxycytidine is a nucleoside composed of a deoxyribose sugar and cytosine, distinguished by the absence of a hydroxyl group at the 2′ position of the ribose. This modification makes it an essential component of DNA, where it pairs with guanine during base pairing. 2′-Deoxycytidine plays significant roles in cellular metabolism and DNA synthesis, serving as a building block for deoxycytidine triphosphate (dCTP), which is crucial for DNA replication and repair. Additionally, this nucleoside has important implications in molecular biology research, cancer therapy, and antiviral strategies, highlighting its relevance in both fundamental research and clinical applications.
-
2,2′-cyclouridine CAS:3736-77-4
2,2′-Cyclouridine is a bicyclic nucleoside derivative of uridine, characterized by the formation of a unique cyclic structure involving the 2′ and 2” positions of the ribose moiety. This structural modification imparts distinct biochemical properties that influence its stability and biological activity. 2,2′-Cyclouridine has garnered interest in chemical biology and medicinal chemistry due to its potential applications as an antiviral agent and in RNA research. Its ability to modulate nucleic acid interactions makes it a valuable tool for studying RNA structure-function relationships, potentially leading to advancements in therapeutic strategies targeting viral infections and genetic diseases.
-
2-Aminoadenosine CAS:2096-10-8
2-Aminoadenosine is a naturally occurring nucleoside derivative of adenosine, distinguished by the presence of an amino group at the 2-position of the ribose sugar. This modification significantly alters its biochemical properties and functions, making it an essential molecule in various physiological processes. 2-Aminoadenosine is involved in cellular signaling, metabolism, and regulatory pathways, including those related to energy homeostasis and neurotransmission. Its potential therapeutic applications span multiple fields, including neurobiology and cardiology, where it may influence cellular responses to stress and injury. As research continues, 2-aminoadenosine holds promise for developing novel bioactive compounds and therapeutic agents.
-
2′-Deoxyuridine CAS:951-78-0
2′-Deoxyuridine is a nucleoside derived from uridine, with the distinguishing feature of having a hydrogen atom instead of a hydroxyl group at the 2′ position of the ribose sugar. This modification renders it a crucial building block in the synthesis of DNA, where it pairs with adenine during base pairing. 2′-Deoxyuridine plays a significant role in cellular metabolism and DNA replication. Additionally, it serves as a precursor for the synthesis of deoxythymidine and has applications in molecular biology research, cancer therapy, and antiviral strategies. Its unique properties make it an important compound in both fundamental and applied research.
-
TERT-BUTYL ISOCYANIDE CAS:7188-38-7
tert-Butyl isocyanide (also known as 2-isocyanobutane) is an organic compound with the chemical formula C₄H₉N. It features a branched tert-butyl group attached to an isocyanide functional group (–N≡C). This unique structure imparts significant reactivity, making it a valuable intermediate in organic synthesis. tert-Butyl isocyanide is primarily utilized in the preparation of various nitrogen-containing compounds, including pharmaceuticals and agrochemicals. Its distinctive properties enable it to participate in several important reactions, making it a useful tool for chemists in the development of novel materials and bioactive molecules.
-
p-Toluenesulfonyl Isocyanate CAS:4083-64-1
p-Toluenesulfonyl isocyanate (PTSI) is an organic compound with the chemical formula C₉H₉N₂O₂S. It features a p-toluenesulfonyl group attached to an isocyanate functional group, making it a valuable reagent in organic synthesis and material science. PTSI is known for its high reactivity and selectivity, particularly in coupling reactions and the synthesis of urea derivatives. Its applications extend to pharmaceuticals, agrochemicals, and polymer chemistry. The unique properties of p-toluenesulfonyl isocyanate make it an essential tool for chemists seeking to develop novel compounds with specific functionalities.
