D-serine is a non-proteinogenic amino acid serving as a crucial neuromodulator in the central nervous system. It acts as a co-agonist at the glycine site of N-methyl-D-aspartate (NMDA) receptors, playing a significant role in synaptic plasticity, learning, and memory processes. Additionally, it participates in neurodevelopment and various physiological functions, making it a subject of extensive research in the fields of neuroscience, pharmacology, and psychiatry.