Pyridoxal-5′-phosphate monohydrate CAS:41468-25-1

Pyridoxal-5′-phosphate monohydrate, also known as PLP, is the active form of vitamin B6. It is an essential coenzyme involved in a wide range of enzymatic reactions in the body. PLP plays a vital role in amino acid metabolism, neurotransmitter synthesis, and the synthesis of heme, a component of hemoglobin.

PLP functions as a coenzyme by binding to specific enzymes and aiding in chemical reactions. It acts as a catalyst, facilitating the conversion of various substances, such as amino acids, into different products. PLP is particularly important in the metabolism of amino acids, such as the conversion of tryptophan into serotonin, or the breakdown of glycine into serine.

In addition to its role in amino acid metabolism, PLP is also involved in the synthesis of neurotransmitters like dopamine, norepinephrine, and gamma-aminobutyric acid (GABA). These neurotransmitters are essential for proper brain function and are involved in mood regulation, cognition, and the transmission of signals between nerve cells.

Furthermore, PLP is necessary for the synthesis of heme, a component of hemoglobin found in red blood cells. Hemoglobin is responsible for carrying oxygen throughout the body, making PLP crucial for maintaining normal oxygen levels and ensuring proper functioning of various organs and tissues.

Due to its importance in numerous biochemical processes, PLP supplementation is sometimes recommended for individuals with certain medical conditions or deficiencies that affect vitamin B6 metabolism. It is available in supplement form and can be prescribed by healthcare providers for specific needs.