(R)-(4-Fluorophenyl)oxirane CAS:134356-73-3

As a versatile building block, this enantiopure epoxide facilitates efficient synthesis of pharmaceuticals and functional materials. Nucleophilic ring-openings on the oxirane introduce valuable hydroxyl derivatives for biological screening and medicinal chemistry efforts. The ring-opening products lend themselves to further manipulations, systematically generating focused compound libraries. Additionally, the aromatic fluorine renders this suitable for metal-catalyzed cross-couplings, furnishing heterocyclic libraries. The epoxide also serves as a monomer for producing specialty polymers with controlled solubility and chirality. Optically pure materials find widespread use as coatings and separators. Moreover, oxirane ring-opening followed by functional group transformations provides access to crop protection agents. Therefore, with multiple points of diversity and an integral stereogenic center, this synthon supports versatile enantioselective synthesis of drugs, agrochemicals, and functional materials.