Rifampicin CAS:13292-46-1

Rifampicin is a key drug in the treatment of tuberculosis, particularly multidrug-resistant tuberculosis (MDR-TB) and latent tuberculosis infections. It is often combined with other antibiotics like isoniazid and pyrazinamide to create a comprehensive regimen that targets different stages of the tuberculosis-causing bacteria, Mycobacterium tuberculosis. In addition to tuberculosis, rifampicin is used in the management of leprosy, methicillin-resistant Staphylococcus aureus (MRSA) infections, and certain cases of meningococcal carriers. Its ability to penetrate tissues and biofilms makes rifampicin effective in treating chronic and biofilm-related infections caused by various bacteria. Healthcare providers may also prescribe rifampicin for prophylactic purposes, such as post-exposure prophylaxis for individuals at risk of contracting meningococcal disease or for preventing the spread of tuberculosis in close contacts of infected individuals. Patients taking rifampicin should be monitored for potential side effects, including hepatotoxicity, gastrointestinal disturbances, and drug interactions due to its induction of hepatic enzymes. Regular liver function tests and clinical assessments are essential to ensure the safe and effective use of rifampicin in the management of bacterial infections.