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(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine CAS:132335-44-5

(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine is a chiral compound with significant pharmacological importance. It belongs to the class of β-adrenergic receptor antagonists, commonly known as beta-blockers. This compound exhibits a unique structural arrangement with a thienyl group and a hydroxy-functionalized chiral center, imparting distinct biological activities. Beta-blockers like (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine are widely used in the management of cardiovascular diseases, including hypertension, angina, and arrhythmias, by blocking the effects of adrenaline on beta receptors in the heart and blood vessels. The chirality of this compound is crucial as the enantiomers may exhibit different pharmacological effects due to interactions with specific receptors in the body.


Product Detail

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Application and Effect:

The synthesis and study of (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine have garnered interest in the pharmaceutical and chemical research fields. The enantioselective synthesis of this compound is challenging but crucial to access pure enantiomers for studying their pharmacological activities. Researchers have developed various synthetic routes utilizing chiral resolving agents or asymmetric catalysts to obtain the desired enantiomer. Studies have shown that the (S)-enantiomer of beta-blockers like (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine may exhibit higher affinity and selectivity towards beta-adrenergic receptors compared to the (R)-enantiomer, making it a promising candidate for further drug development. Further research on the pharmacological properties and therapeutic potential of (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine is warranted to explore its efficacy and safety profile in clinical settings. Understanding the structure-activity relationship of this compound and its interactions with beta receptors can lead to the development of novel beta-blockers with improved therapeutic outcomes and reduced side effects. Overall, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine represents a valuable chemical entity in the realm of pharmaceutical research, offering insights into the design and development of cardiovascular drugs with enhanced pharmacological properties.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C9H15NOS
Assay 99%
Appearance white powder
CAS No.  132335-44-5
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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