Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Manufacturer Supplier
Sodium Alpha-Ketoisocaproate is a leucine metabolite that is known to induce insulin secretion from the βcells of pancreas. Enteral infusion of aα-Ketoisocaproate is found to ameliorate, endotoxemic condition. The resulting ketone bodies obtained from its conversion, might serve as an energy source. Accumulation of α-Ketoisocaproic acid is characterized in branched chain ketoaciduria, which is caused due to the lack of branched chain L-2-keto acid dehydrogenase activity. α-Ketoisocaproic acid causes dissociation in the oxidative phosphorylation reaction and acts as a metabolic inhibitor of α-ketoglutarate dehydrogenase. Thus, leads to a defect in the mitochondrial homeostasis, observed in branched chain ketoaciduria.
Composition | C6H9NaO3 |
Assay | 99% |
Appearance | White to Off-White powder |
CAS No. | 4502-00-5 |
Packing | 25KG |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |
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