Strontium ranelate CAS:135459-87-9

Strontium ranelate is primarily used in the management of osteoporosis, a condition characterized by weakened bones prone to fractures. Here are its key uses: Osteoporosis Treatment: Strontium ranelate is prescribed to postmenopausal women and men with osteoporosis to reduce the risk of fractures. It works by stimulating bone formation by osteoblasts (cells responsible for bone synthesis) and reducing bone resorption by osteoclasts (cells responsible for bone breakdown), leading to improved bone density. Fracture Prevention: The primary goal of strontium ranelate treatment is to prevent fractures, especially in individuals at high risk due to osteoporosis. By strengthening bones, it reduces the likelihood of fractures, particularly in the hip and spine, which are common sites of osteoporotic fractures. Bone Mineral Density (BMD) Improvement: Strontium ranelate has been shown to increase bone mineral density, a key factor in assessing bone strength. By improving BMD, it helps reduce the risk of fractures and maintains skeletal health. Postmenopausal Osteoporosis: Women after menopause are at increased risk of osteoporosis due to hormonal changes. Strontium ranelate is often prescribed in this population to mitigate bone loss and reduce fracture risk. Bone Health Maintenance: In addition to treating osteoporosis, strontium ranelate may be used as a maintenance therapy to sustain bone health and prevent further bone loss in individuals with osteopenia (low bone mass) or those at risk of developing osteoporosis. Alternative to Bisphosphonates: Strontium ranelate offers an alternative treatment option for osteoporosis, particularly for individuals who cannot tolerate or have contraindications to bisphosphonates, another class of drugs used in osteoporosis management. Clinical Research: Ongoing research explores the efficacy and safety of strontium ranelate in various populations, including older adults and those with specific health conditions affecting bone health. Combination Therapy: In some cases, strontium ranelate may be used in combination with other osteoporosis medications to enhance bone health outcomes, especially in individuals with severe osteoporosis or multiple risk factors for fractures. In summary, strontium ranelate is an important medication in the management of osteoporosis, offering a dual-action approach to improve bone density and reduce fracture risk. Its use is well-established in postmenopausal women and men with osteoporosis, providing an effective treatment option for maintaining skeletal health.