Tetracycline hydrochloride CAS:64-75-5

Tetracycline hydrochloride finds applications in the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, sexually transmitted diseases, and atypical infections such as Lyme disease and acne vulgaris. It is also utilized in managing conditions like periodontal disease and Helicobacter pylori eradication therapy. The dosage and administration of tetracycline hydrochloride are similar to tetracycline, with considerations for the type and severity of the infection, patient's age, weight, and renal function. It is typically administered orally, either as tablets or capsules, preferably on an empty stomach to optimize absorption. However, some formulations may be taken with food to minimize gastrointestinal irritation. Patients should be cautioned about potential side effects associated with tetracycline therapy, including gastrointestinal disturbances, photosensitivity reactions, and tooth discoloration, particularly in pediatric and pregnant populations. Due to the risk of tooth discoloration and impaired bone development, tetracycline hydrochloride is contraindicated in pregnant women, nursing mothers, and children under eight years of age. Avoiding concurrent intake of tetracycline hydrochloride with dairy products, antacids, or iron supplements is recommended, as they can impair its absorption. Prolonged use may lead to bacterial resistance and superinfections. Regular monitoring for adverse effects and consultation with healthcare professionals for personalized treatment recommendations are essential to ensure safe and effective use of tetracycline hydrochloride in bacterial infections.