Thrombin CAS:9002-04-4 Manufacturer Price

Thrombin is a key enzyme involved in blood clotting, also known as coagulation. It is produced from its precursor protein, prothrombin, in response to injury or damage to blood vessels. Thrombin plays a crucial role in the formation of a blood clot, which helps to prevent excessive bleeding and promote wound healing.

Once activated, thrombin converts fibrinogen, another protein in the blood, into fibrin. Fibrin forms a mesh-like structure that traps platelets and red blood cells, forming a stable blood clot. Thrombin also activates other coagulation factors, amplifying the clotting process.

Beyond its role in clot formation, thrombin has other important functions. It promotes wound healing by stimulating the migration and proliferation of cells involved in tissue repair. Thrombin also acts as a vasoconstrictor, causing blood vessels to narrow and reduce blood flow to the site of injury.

Order or Request Quote

Product Detail

Product Tags

Application and Effect

Effects of Thrombin:

Blood Clotting: Thrombin plays a central role in the blood clotting process, as it converts fibrinogen into fibrin, which forms a mesh-like network that helps in the formation and stabilization of blood clots.

Platelet Activation: Thrombin activates platelets, promoting their aggregation and adhesion to the site of injury, further aiding in the formation of a clot.

Vasoconstriction: Thrombin causes blood vessels to constrict, reducing blood flow at the site of injury and contributing to hemostasis.

Applications of Thrombin:

Diagnostic Tests: Thrombin is used in various laboratory tests to assess blood clotting function, including the prothrombin time (PT) and activated partial thromboplastin time (aPTT) assays.

Hemostasis and Surgical Procedures: Thrombin can be applied topically as a gel or powder to promote hemostasis and control bleeding during surgical procedures. It is particularly useful in cases where conventional methods may be ineffective or impractical.

Wound Healing: Thrombin has been studied for its potential role in wound healing. It can stimulate the migration and proliferation of cells involved in tissue repair, such as fibroblasts and endothelial cells.

Anticoagulant Reversal: In emergency situations where there is excessive bleeding due to anticoagulant medication use, thrombin can be administered to aid in the rapid reversal of anticoagulant effects.